Bio, Medical, and Drug Discovery
Dispensing Solutions
High-precision dispensing technology is utilized in all fields that handle liquids, including pharmaceuticals, cosmetics, and the bio/analytical industries. MUSASHI undertakes the production of automated dispensing equipment required in various manufacturing and research fields. Automating manual tasks helps reduce costs and labor, prevent errors, and improve work accuracy.
Pre-analysis processing
Analytical pretreatment is a series of operations to prepare samples into an appropriate state before analysis. In this process, it is extremely important to ensure measurement accuracy and reproducibility, and to optimize samples according to the characteristics of the equipment and methods. We support protocols for small volumes (µL to mL) while minimizing dead volume.
Main processes of analytical pretreatment
Samples are aliquoted using appropriate methods, and the target analytes are preserved. We semi-automate the sampling process for aliquoting synthesized products from organic synthesis equipment. Its compact and simple design allows for integration into various types of equipment.
The task of dividing samples into fixed amounts. High-precision dispensing influences the reproducibility of analysis results.
Our products support both liquid and powder samples, fully automating everything from tip attachment to dispensing. Dispensing volumes can be set individually for each pipette. They are compatible with various containers such as microtubes, plates, and vials.
System Example
Adjusting multiple types of samples to appropriate concentrations.
Dilution amounts and dilution ratios can be set easily. A stirring function enables mixing operations. Since analysis equipment racks can be loaded directly, the workflow leading up to analysis is seamless.
System Example
A camera recognizes the graduation mark on a volumetric flask, and the meniscus position is automatically and accurately aligned with the mark, reducing variations in positioning caused by operators.
System Example
Analytical Pretreatment Product Quick Reference Table
| Products | Organic Synthesis Extraction System |
Variable Pitch 4-Channel PIPET MASTER  |
Dispensing and Dilution System |
Formulation System |
Liquid volume adjustment system |
|---|---|---|---|---|---|
| Dispensing/ Filling Volume |
up to 50mL | 0.5μL to 1mL | Specimen: ~10mL Diluent: ~50mL |
Pipette head: 0.5~20mL Syringe pump: ~50mL |
Compatible with 10 mL to 250 mL |
| Dispensing/ Filling Method |
Volumetric | Volumetric measurement | Volumetric measurement | Volumetric measurement | Pump type |
| Contamination prevention mechanism |
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Pipette head: Automatic tip attachment/detachment |
Pipette head: Automatic tip attachment/detachment |
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| Sample collection |
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| Dispensing |
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| Dilution |
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| Multi-channel specification |
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Reagent Spotting
This is the process of applying specific reagents to the surface of materials or devices used for testing or experiments. In the modern biotechnology field, where miniaturization of samples and reproducibility are required, dispensers are an essential technology.
This is the process of accurately applying a minute amount of liquid sample onto a specific substrate (such as a slide glass or microplate). It is used in various scenarios, including pharmacological screening, antibody testing, and DNA microarrays.
Our company enables ultra-micro (nL) spotting of a wide variety of reagents. We prevent contamination and achieve high-precision, high-speed application. It offers high reproducibility and spots samples uniformly at precise locations.
System Example
Reagent Spotting Product Quick Reference Table
| Products | SPOT MASTER  |
8-Channel JET SPOTTER |
|---|---|---|
| Dispensing/ Filling Volume |
1nL~120μL | Several nL~ |
| Dispensing/ Filling Method |
Volumetric | Jet type |
| Contamination prevention mechanism |
Nozzle washing and drying type |
Nozzle washing and drying type |
| Line |
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| Spotting |
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| Multi-channel specification |
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Reagent filling
Filling refers to the process of dispensing a fixed amount of liquid or powdered reagent into appropriate containers and sealing them. It is frequently used in the manufacturing of diagnostic agents, medical reagents, research reagents, or bio-products. Reagent filling requires strict control to stabilize product quality and enable accurate use.
Filling and capping are processes performed sequentially to seal liquid medicine into containers and protect it from the external environment.
A single robot consolidates the entire sequence of operations: "opening the cap → filling the liquid medicine → closing the cap." This ensures efficient production and product uniformity.
Powdered materials are filled into appropriate containers and measured in precise amounts. Weight is monitored in real-time, allowing for OK/NG judgment based on weight discrepancies and log management of weighing values.
Reagent Filling Product Quick Reference Table
| Products | Liquid Filling & Capping System (Pipette Type)  |
POWDER SHOT & Weighing System  |
|---|---|---|
| Dispensing volume | 0.5 μL to 20 mL | Several μL to 5000 μL |
| Dispensing method | Volumetric | — |
| Contamination prevention mechanism |
Pipette tip automatic attachment/detachment |
Automatic tip attachment/detachment |
| Capping |
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| Weighing |
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Supports mass production
In high-throughput screening (HTS) and large-scale experiments, it is necessary to rapidly dispense large quantities of reagents and samples. Fully automated dispensing machines allow for efficient workflow. By working with the minimum necessary volume, costs can be reduced. Furthermore, it prevents the need to redo tests due to dispensing errors.
FAD2500SD
| Dispensing volume | 0.5μL~ |
| Dispensing method | ※ |
| Contamination prevention mechanism |
※ |
| Weighing |
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| Log Management |
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*Varies depending on the mounted head.
